Carpal Tunnel Syndrome 

Pathophysiology

  • Compression of the median nerve within the carpal tunnel compartment at the wrist
  • RFs: Repetitive activities (gardening, painting etc), obesity, pregnancy, arthritis, DM
Figure 229: The Carpal Tunnel. OpenStax College, CC BY 3.0.

Clinical features

  • Sensory: Intermittent paraesthesia, sensory changes, or neuropathic pain in the distribution of the median nerve (lateral 2/3 palm and lateral 3.5 fingers, thenar eminence).
  • Motor: Reduced grip strength or loss of dexterity 
  • Symptoms are often worse during the night, often disturbing sleep
  • Patients may shake their hands to relieve the pain
  • Examination:
    • Phalen’s test - wrist flexion causes symptoms
    • Tinel’s test - taping over median nerve reproduces symptoms 
    • Wasting of thenar muscles, weakness and sensory changes as above
Figure 230: Thenar wasting in a patient with untreated carpal tunnel syndrome.

Investigations

  • CTS is a clinical diagnosis, but nerve conduction studies can be performed for confirmation.

Management

  • Mild-moderate symptoms - try the following:
    • Wrist splint
    • Corticosteroid injection into the carpal tunnel
  • If symptoms are severe or persistent despite the above, refer for specialist management:
    • Nerve conduction studies
    • Carpal tunnel decompression surgery

Cubital Tunnel Syndrome 

Pathophysiology

  • Compression of the ulnar nerve in the cubital tunnel (between the medial epicondyle of the humerus to the olecranon process of the ulna). 

Clinical features

  • Pain around the medial elbow, or in the forearm.  
  • Sensory: Intermittent paraesthesia, sensory changes, or neuropathic pain in the distribution of the ulnar nerve (medial 1/3rd hand, hypothenar eminence, medial 1.5 fingers)
  • Atrophy of the intrinsic muscles of the hand, claw hand may be present 
  • Positive elbow flexion test, or pressure provocative test. Tinel’s positive taping at the cubital tunnel. 
Figure 231: The ulnar tunnel - a site of entrapment ulnar neuropathy. InjuryMap, CC BY-SA 4.0.

Radial Tunnel Syndrome 

Pathophysiology

  • Compression of the posterior interosseous nerve (deep branch of the radial nerve) 

Clinical features

  • Vague pain at the top of the forearm, which is worst a few cm proximal to the lateral epicondyle, may radiate down to the wrist
  • Pain is worse on pronation of the forearm
  • Pain is often more severe at night, disturbing sleep
  • On examination, extension of the thumb and index finger against resistance may replicate pain