Ganglion cysts are one of the most common benign soft tissue masses affecting the hand and wrist, originating from the synovial lining of joints and tendons.
Aetiology
- The most common cause of lumps on the hand and wrist, originating from the synovial lining of joints and tendons, which produces lubricating fluid.
- These cysts are typically pulsion diverticulae - herniation of the synovium.
- The exact cause is unknown.
- Myxoid or mucous cysts are a sub-type of ganglion, commonly associated with arthritis. They are commonly present around the proximal nail fold. A clear fluid may be expressed.

Clinical features
- Usually asymptomatic unless large enough to exert pressure or impair joint function.
- On examination, they are smooth swellings, often found:
- On the back or front of the wrist, base of the fingers or back of the fingers near the joints.
- They transilluminate, reflecting their fluid contents, which helps differentiate them from other types of lump.

Management
- Treatment is generally only recommended by if the cyst is causing significant pain or affecting the range of movement of a joint.
- They often resolve without intervention.
- If required, management options include:
- Aspiration - high recurrence rate.
- Surgery: Open surgery or arthroscopic removal of the cyst.